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The Use of Murine Models for Studying Mechanistic Insights of Genomic Instability in Multiple Myeloma
Multiple myeloma (MM) is a B-cell malignancy characterized by the accumulation of clonal plasma cells in the bone marrow. In normal plasma cell development, cells undergo programmed DNA breaks and translocations, a process necessary for generation of a wide repertoire of antigen-specific antibodies....
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| Publicado no: | Front Genet |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6704229/ https://ncbi.nlm.nih.gov/pubmed/31475039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00740 |
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