Targeted deletion of hepatocyte Abca1 increases plasma HDL reverse cholesterol transport via the LDL receptor

OBJECTIVE: The role of hepatocyte ATP binding cassette transporter A1 (Abca1) in trafficking hepatic free cholesterol (FC) into plasma versus bile for reverse cholesterol transport (RCT) is poorly understood. We hypothesized that hepatocyte Abca1 recycles plasma HDL cholesterol (HDL-C) taken up by t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arterioscler Thromb Vasc Biol
Prif Awduron: Bashore, Alexander C., Liu, Mingxia, Key, Chia-Chi C., Boudyguina, Elena, Wang, Xianfeng, Carroll, Caitlin M., Sawyer, Janet K., Mullick, Adam E., Lee, Richard G., Macauley, Shannon L., Parks, John S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703909/
https://ncbi.nlm.nih.gov/pubmed/31167565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.312382
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