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Quantitative prediction of erythrocyte sickling for the development of advanced sickle cell therapies
Sickle cell disease is induced by a mutation that converts normal adult hemoglobin to sickle hemoglobin (HbS) and engenders intracellular polymerization of deoxy-HbS and erythrocyte sickling. Development of anti-sickling therapies requires quantitative understanding of HbS polymerization kinetics un...
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| Publicado no: | Sci Adv |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6703859/ https://ncbi.nlm.nih.gov/pubmed/31457104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax3905 |
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