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Effect of Chain Chirality on the Self-Assembly of Sickle Hemoglobin

We present simulation results on the self-assembly behavior of sickle hemoglobin (HbS). A coarse-grained HbS model, which contains hydrophilic and hydrophobic particles explicitly, is constructed to match the structural properties and physical description of HbS. The hydrophobic interactions are sho...

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Bibliografiske detaljer
Main Authors: Li, Xuejin, Caswell, Bruce, Karniadakis, George Em
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446663/
https://ncbi.nlm.nih.gov/pubmed/22995485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.08.017
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