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Both Ligands and Macromolecular Crowders Preferentially Bind to Closed Conformations of Maltose Binding Protein

In cellular environments, proteins not only interact with their specific partners but also encounter a high concentration of bystander macromolecules, or crowders. Nonspecific interactions with macromolecular crowders modulate the activities of proteins, but our knowledge about the rules of nonspeci...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Ghosh, Archishman, Smith, Pieter E. S., Qin, Sanbo, Yi, Myunggi, Zhou, Huan-Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703856/
https://ncbi.nlm.nih.gov/pubmed/30950267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00154
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