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Genetic Ablation of Hypocretin Neurons Alters Behavioral State Transitions in Zebrafish

Sleep is an essential biological need of all animals studied to date. The sleep disorder narcolepsy is characterized by excessive daytime sleepiness, fragmentation of nighttime sleep, and cataplexy. Narcolepsy is caused by selective degeneration of hypothalamic hypocretin/orexin (HCRT) neurons. In m...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Elbaz, Idan, Yelin-Bekerman, Laura, Nicenboim, Julian, Vatine, Gad, Appelbaum, Lior
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703801/
https://ncbi.nlm.nih.gov/pubmed/22973020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1284-12.2012
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