Sleep–wake regulation and hypocretin–melatonin interaction in zebrafish

In mammals, hypocretin/orexin (HCRT) neuropeptides are important sleep–wake regulators and HCRT deficiency causes narcolepsy. In addition to fragmented wakefulness, narcoleptic mammals also display sleep fragmentation, a less understood phenotype recapitulated in the zebrafish HCRT receptor mutant (...

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Bibliographische Detailangaben
Hauptverfasser: Appelbaum, Lior, Wang, Gordon X., Maro, Geraldine S., Mori, Rotem, Tovin, Adi, Marin, Wilfredo, Yokogawa, Tohei, Kawakami, Koichi, Smith, Stephen J., Gothilf, Yoav, Mignot, Emmanuel, Mourrain, Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799794/
https://ncbi.nlm.nih.gov/pubmed/19966231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.906637106
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