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Cdc42 defines apical identity and regulates epithelial morphogenesis by promoting apical recruitment of Par6-aPKC and Crumbs

Cdc42 regulates epithelial morphogenesis together with the Par complex (Baz/Par3-Par6-aPKC), Crumbs (Crb/CRB3) and Stardust (Sdt/PALS1). However, how these proteins work together and interact during epithelial morphogenesis is not well understood. To address this issue, we used the genetically amena...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Nunes de Almeida, Francisca, Walther, Rhian F., Pressé, Mary T., Vlassaks, Evi, Pichaud, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703713/
https://ncbi.nlm.nih.gov/pubmed/31405903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.175497
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