Imaging Microglial/Macrophage Activation in Spinal Cords of Experimental Autoimmune Encephalomyelitis Rats by Positron Emission Tomography Using the Mitochondrial 18 kDa Translocator Protein Radioligand [(18)F]DPA-714

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS. Activated microglia/macrophages play a key role in the immunopathogenesis of MS and its corresponding animal models, experimental autoimmune encephalomyelitis (EAE). Microglia activation begins at early stages of the diseas...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Abourbeh, Galith, Thézé, Benoit, Maroy, Renaud, Dubois, Albertine, Brulon, Vincent, Fontyn, Yoann, Dollé, Frédéric, Tavitian, Bertrand, Boisgard, Raphaël
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703630/
https://ncbi.nlm.nih.gov/pubmed/22539835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2900-11.2012
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