Evaluation of the PBR/TSPO radioligand [(18)F]DPA-714 in a rat model of focal cerebral ischemia

Focal cerebral ischemia leads to an inflammatory reaction involving an overexpression of the peripheral benzodiazepine receptor (PBR)/18-kDa translocator protein (TSPO) in the cerebral monocytic lineage (microglia and monocyte) and in astrocytes. Imaging of PBR/TSPO by positron emission tomography (...

Full description

Saved in:
Bibliographic Details
Main Authors: Martín, Abraham, Boisgard, Raphaël, Thézé, Benoit, Van Camp, Nadja, Kuhnast, Bertrand, Damont, Annelaure, Kassiou, Michael, Dollé, Frédéric, Tavitian, Bertrand
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949091/
https://ncbi.nlm.nih.gov/pubmed/19794397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.205
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items