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Small Heat-Shock Protein HSPB1 Mutants Stabilize Microtubules in Charcot-Marie-Tooth Neuropathy
Mutations in the small heat shock protein HSPB1 (HSP27) are causative for Charcot-Marie-Tooth (CMT) neuropathy. We previously showed that a subset of these mutations displays higher chaperone activity and enhanced affinity to client proteins. We hypothesized that this excessive binding property migh...
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| Published in: | J Neurosci |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Society for Neuroscience
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6703512/ https://ncbi.nlm.nih.gov/pubmed/22031878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3266-11.2011 |
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