TRPM2 Contributes to Inflammatory and Neuropathic Pain through the Aggravation of Pronociceptive Inflammatory Responses in Mice

Accumulating evidence suggests that neuroimmune interactions contribute to pathological pain. Transient receptor potential melastatin 2 (TRPM2) is a nonselective Ca(2+)-permeable cation channel that acts as a sensor for reactive oxygen species. TRPM2 is expressed abundantly in immune cells and is im...

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Vydáno v:J Neurosci
Hlavní autoři: Haraguchi, Kayo, Kawamoto, Ai, Isami, Kouichi, Maeda, Sanae, Kusano, Ayaka, Asakura, Kayoko, Shirakawa, Hisashi, Mori, Yasuo, Nakagawa, Takayuki, Kaneko, Shuji
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703465/
https://ncbi.nlm.nih.gov/pubmed/22423113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4703-11.2012
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