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Interferon pathway in SLE: one key to unlocking the mystery of the disease

SLE is characterised by an activation of the interferon (IFN) system, which leads to an increased expression of IFN-regulated genes. The reasons behind the IFN signature in SLE are (1) the existence of endogenous IFN inducers, (2) activation of several IFN-producing cell types, (3) production of man...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Lupus Sci Med
Main Authors: Rönnblom, Lars, Leonard, Dag
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703304/
https://ncbi.nlm.nih.gov/pubmed/31497305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/lupus-2018-000270
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