Characterization of 3,4-Methylenedioxymethamphetamine (MDMA) Enantiomers In Vitro and in the MPTP-Lesioned Primate: R-MDMA Reduces Severity of Dyskinesia, Whereas S-MDMA Extends Duration of ON-Time

l-3,4-Dihydroxyphenylalanine (l-DOPA) is the most effective treatment for Parkinson's disease, but long-term l-DOPA administration is marred by the emergence of motor complications, namely, dyskinesia and a shortening of antiparkinsonian benefit (wearing-OFF). 3,4-Methylenedioxymethamphetamine...

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發表在:J Neurosci
Main Authors: Huot, Philippe, Johnston, Tom H., Lewis, Katie D., Koprich, James B., Reyes, M. Gabriela, Fox, Susan H., Piggott, Matthew J., Brotchie, Jonathan M.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2011
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703214/
https://ncbi.nlm.nih.gov/pubmed/21562283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1171-11.2011
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