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Heterologous Expression of L. major proteins in S. cerevisiae: a test of solubility, purity, and gene recoding

High level expression of many eukaryotic proteins for structural analysis is likely to require a eukaryotic host since many proteins are either insoluble or lack essential post-translational modifications when expressed in E. coli. The well-studied eukaryote Saccharomyces cerevisiae possesses severa...

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Detalhes bibliográficos
Publicado no:J Struct Funct Genomics
Main Authors: Quartley, Erin, Alexandrov, Andrei, Mikucki, Maryann, Buckner, Frederick S., Hol, Wim G., DeTitta, George T., Phizicky, Eric M., Grayhack, Elizabeth J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703162/
https://ncbi.nlm.nih.gov/pubmed/19701618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10969-009-9068-9
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