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Protopanaxadiol inhibits epithelial–mesenchymal transition of hepatocellular carcinoma by targeting STAT3 pathway

Diol-type ginsenosides, such as protopanaxadiol (PPD), exhibit antioxidation, anti-inflammation, and antitumor effects. However, the antitumor effect of these ginsenosides and the mechanism of PPD remain unclear. In this work, the antitumor effects of several derivatives, including PPD, Rg5, Rg3, Rh...

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Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Yang, Lan, Zhang, Xue-ying, Li, Kun, Li, An-ping, Yang, Wen-dong, Yang, Ru, Wang, Peng, Zhao, Zi-han, Cui, Fang, Qin, Yuan, Yang, Jia-huan, Tao, Hong-lian, Sun, Tao, Chen, Shuang, Yu, Pei-hua, Liu, Hui-juan, Yang, Cheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702205/
https://ncbi.nlm.nih.gov/pubmed/31431619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1733-8
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