Protopanaxadiol inhibits epithelial–mesenchymal transition of hepatocellular carcinoma by targeting STAT3 pathway

Diol-type ginsenosides, such as protopanaxadiol (PPD), exhibit antioxidation, anti-inflammation, and antitumor effects. However, the antitumor effect of these ginsenosides and the mechanism of PPD remain unclear. In this work, the antitumor effects of several derivatives, including PPD, Rg5, Rg3, Rh...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yang, Lan, Zhang, Xue-ying, Li, Kun, Li, An-ping, Yang, Wen-dong, Yang, Ru, Wang, Peng, Zhao, Zi-han, Cui, Fang, Qin, Yuan, Yang, Jia-huan, Tao, Hong-lian, Sun, Tao, Chen, Shuang, Yu, Pei-hua, Liu, Hui-juan, Yang, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702205/
https://ncbi.nlm.nih.gov/pubmed/31431619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1733-8
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