Protopanaxadiol inhibits epithelial–mesenchymal transition of hepatocellular carcinoma by targeting STAT3 pathway

Diol-type ginsenosides, such as protopanaxadiol (PPD), exhibit antioxidation, anti-inflammation, and antitumor effects. However, the antitumor effect of these ginsenosides and the mechanism of PPD remain unclear. In this work, the antitumor effects of several derivatives, including PPD, Rg5, Rg3, Rh...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Yang, Lan, Zhang, Xue-ying, Li, Kun, Li, An-ping, Yang, Wen-dong, Yang, Ru, Wang, Peng, Zhao, Zi-han, Cui, Fang, Qin, Yuan, Yang, Jia-huan, Tao, Hong-lian, Sun, Tao, Chen, Shuang, Yu, Pei-hua, Liu, Hui-juan, Yang, Cheng
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702205/
https://ncbi.nlm.nih.gov/pubmed/31431619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1733-8
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