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Transcriptional Bursts in a Nonequilibrium Model for Gene Regulation by Supercoiling
We analyze transcriptional bursting within a stochastic nonequilibrium model, which accounts for the coupling between the dynamics of DNA supercoiling and gene transcription. We find a clear signature of bursty transcription when there is a separation between the timescales of transcription initiati...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6702136/ https://ncbi.nlm.nih.gov/pubmed/31103229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.04.023 |
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