A Structural Model of the Inactivation Gate of Voltage-Activated Potassium Channels

After opening, the Shaker voltage-gated potassium (K(V)) channel rapidly inactivates when one of its four N-termini enters and occludes the channel pore. Although it is known that the tip of the N-terminus reaches deep into the central cavity, the conformation adopted by this domain during inactivat...

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Bibliographic Details
Published in:Biophys J
Main Authors: Vergara-Jaque, Ariela, Palma-Cerda, Francisco, Lowet, Adam S., de la Cruz Landrau, Angel, Poblete, Horacio, Sukharev, Alexander, Comer, Jeffrey, Holmgren, Miguel
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702135/
https://ncbi.nlm.nih.gov/pubmed/31278002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.06.008
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