Serial synapse formation through filopodial competition for synaptic seeding factors

Following axon pathfinding, growth cones transition from stochastic filopodial exploration to the formation of a limited number of synapses. How the interplay of filopodia and synapse assembly ensures robust connectivity in the brain has remained a challenging problem. Here, we developed a new 4D an...

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Gepubliceerd in:Dev Cell
Hoofdauteurs: Özel, M. Neset, Kulkarni, Abhishek, Hasan, Amr, Brummer, Josephine, Moldenhauer, Marian, Daumann, Ilsa-Maria, Wolfenberg, Heike, Dercksen, Vincent J., Kiral, F. Ridvan, Weiser, Martin, Prohaska, Steffen, von Kleist, Max, Hiesinger, P. Robin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702111/
https://ncbi.nlm.nih.gov/pubmed/31353313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.06.014
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