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Systematic functional analysis of rab GTPases reveals limits of neuronal robustness to environmental challenges in flies

Rab GTPases are molecular switches that regulate membrane trafficking in all cells. Neurons have particular demands on membrane trafficking and express numerous Rab GTPases of unknown function. Here, we report the generation and characterization of molecularly defined null mutants for all 26 rab gen...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Kohrs, Friederike E, Daumann, Ilsa-Maria, Pavlovic, Bojana, Jin, Eugene Jennifer, Kiral, F Ridvan, Lin, Shih-Ching, Port, Filip, Wolfenberg, Heike, Mathejczyk, Thomas F, Linneweber, Gerit A, Chan, Chih-Chiang, Boutros, Michael, Hiesinger, P Robin
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016483/
https://ncbi.nlm.nih.gov/pubmed/33666175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59594
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