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Systematic functional analysis of rab GTPases reveals limits of neuronal robustness to environmental challenges in flies

Rab GTPases are molecular switches that regulate membrane trafficking in all cells. Neurons have particular demands on membrane trafficking and express numerous Rab GTPases of unknown function. Here, we report the generation and characterization of molecularly defined null mutants for all 26 rab gen...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Kohrs, Friederike E, Daumann, Ilsa-Maria, Pavlovic, Bojana, Jin, Eugene Jennifer, Kiral, F Ridvan, Lin, Shih-Ching, Port, Filip, Wolfenberg, Heike, Mathejczyk, Thomas F, Linneweber, Gerit A, Chan, Chih-Chiang, Boutros, Michael, Hiesinger, P Robin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016483/
https://ncbi.nlm.nih.gov/pubmed/33666175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59594
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