Systematic functional analysis of rab GTPases reveals limits of neuronal robustness to environmental challenges in flies

Rab GTPases are molecular switches that regulate membrane trafficking in all cells. Neurons have particular demands on membrane trafficking and express numerous Rab GTPases of unknown function. Here, we report the generation and characterization of molecularly defined null mutants for all 26 rab gen...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Kohrs, Friederike E, Daumann, Ilsa-Maria, Pavlovic, Bojana, Jin, Eugene Jennifer, Kiral, F Ridvan, Lin, Shih-Ching, Port, Filip, Wolfenberg, Heike, Mathejczyk, Thomas F, Linneweber, Gerit A, Chan, Chih-Chiang, Boutros, Michael, Hiesinger, P Robin
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2021
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016483/
https://ncbi.nlm.nih.gov/pubmed/33666175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59594
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