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Complex and Multilayered role of IL-21 signaling during thymic development

Unlike IL-7, which is known to be critical for T cell thymic development, the role of IL-21 in this process is still controversial. IL-21 has been shown to accelerate thymic recovery in mice treated with glucocorticoids and revives the peripheral T cell pool in aged animals. However, mice with a def...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Moretto, Magali M., Hwang, SuJin, Chen, Keer, Khan, Imtiaz A.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702097/
https://ncbi.nlm.nih.gov/pubmed/31341076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800743
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