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IL-21 is important for induction of KLRG1(+) effector CD8 T cells during acute intracellular infection
Microsporidia, a latent opportunistic infection associated with mild inflammation, is characterized by a strong CD8 T cell response, which has been shown to be CD4 T cell dependent. In this manuscript, we demonstrate for the first time that CD4 help is provided via IL-21 production, a common gamma c...
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| Publicado en: | J Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4959448/ https://ncbi.nlm.nih.gov/pubmed/26597007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501258 |
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