The unresolved role of mitochondrial DNA in Parkinson’s disease: an overview of published studies, their limitations, and future prospects

Parkinson’s disease (PD), a progressive neurodegenerative disorder, has long been associated with mitochondrial dysfunction in both sporadic and familial forms of the disease. Mitochondria are crucial for maintaining cellular homeostasis, and their dysfunction is detrimental to dopaminergic neurons....

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Pubblicato in:Neurochem Int
Autori principali: Müller-Nedebock, Amica C., Brennan, Rebecca R., Venter, Marianne, Pienaar, Ilse S., van der Westhuizen, Francois H., Elson, Joanna L., Ross, Owen A., Bardien, Soraya
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702091/
https://ncbi.nlm.nih.gov/pubmed/31233840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2019.104495
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