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The unresolved role of mitochondrial DNA in Parkinson’s disease: an overview of published studies, their limitations, and future prospects

Parkinson’s disease (PD), a progressive neurodegenerative disorder, has long been associated with mitochondrial dysfunction in both sporadic and familial forms of the disease. Mitochondria are crucial for maintaining cellular homeostasis, and their dysfunction is detrimental to dopaminergic neurons....

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Detalhes bibliográficos
Publicado no:Neurochem Int
Main Authors: Müller-Nedebock, Amica C., Brennan, Rebecca R., Venter, Marianne, Pienaar, Ilse S., van der Westhuizen, Francois H., Elson, Joanna L., Ross, Owen A., Bardien, Soraya
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702091/
https://ncbi.nlm.nih.gov/pubmed/31233840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2019.104495
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