Non-NAD-like PARP-1 inhibitors in prostate cancer treatment

In our previous studies of the molecular mechanisms of poly(ADP-ribose) polymerase 1 (PARP-1)-mediated transcriptional regulation we identified a novel class of PARP-1 inhibitors targeting the histone-dependent route of PARP-1 activation. Because histone-dependent activation is unique to PARP-1, non...

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Detaylı Bibliyografya
Yayımlandı:Biochem Pharmacol
Asıl Yazarlar: Karpova, Yaroslava, Wu, Chao, Divan, Ali, McDonnell, Mark E., Hewlett, Elizabeth, Makhov, Peter, Gordon, John, Ye, Min, Reitz, Allen, Childers, Wayne E., Skorski, Tomasz, Kolenko, Vladimir, Tulin, Alexei V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702078/
https://ncbi.nlm.nih.gov/pubmed/30880062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2019.03.021
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