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Charon mediates IMD-driven PARP-1-dependent immune responses in Drosophila

Regulation of NF-kB nuclear translocation and stability is central to mounting an effective innate immune response. Here, we describe a novel molecular mechanism controlling NF-kB-dependent innate immune response. We show that a previously unknown protein, termed as Charon, functions as a regulator...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Ji, Yingbiao, Thomas, Colin, Tulin, Nikita, Lodhi, Niraj, Boamah, Ernest, Kolenko, Vladimir, Tulin, Alexei V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010969/
https://ncbi.nlm.nih.gov/pubmed/27527593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600994
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