Conjugation of an scFab domain to the oligomeric HIV envelope protein for use in immune targeting

A promising strategy for the enhancement of vaccine-mediated immune responses is by directly targeting protein antigens to immune cells. Targeting of antigens to the dendritic cell (DC) molecule Clec9A has been shown to enhance antibody affinity and titers for model antigens, and influenza and enter...

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Опубликовано в: :PLoS One
Главные авторы: King, Hannah A. D., Gonelli, Christopher A., Tullett, Kirsteen M., Lahoud, Mireille H., Purcell, Damian F. J., Drummer, Heidi E., Poumbourios, Pantelis, Center, Rob J.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701830/
https://ncbi.nlm.nih.gov/pubmed/31430333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220986
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