Cross-sectional study into age-related pathology of mouse models for limb girdle muscular dystrophy types 2D and 2F

Limb girdle muscular dystrophy (LGMD) types 2D and 2F are caused by mutations in the genes encoding for α- and δ-sarcoglycan, respectively, leading to progressive muscle weakness. Mouse models exist for LGMD2D (Sgca(-/-)) and 2F (Sgcd(-/-)). In a previous natural history study, we described the path...

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Pubblicato in:PLoS One
Autori principali: Verhaart, Ingrid E. C., Putker, Kayleigh, van de Vijver, Davy, Tanganyika-de Winter, Christa L., Pasteuning-Vuhman, Svetlana, Plomp, Jaap J., Aartsma-Rus, Annemieke M., van Putten, Maaike
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701749/
https://ncbi.nlm.nih.gov/pubmed/31430305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220665
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