Natural disease history of the D2-mdx mouse model for Duchenne muscular dystrophy

The C57BL/10ScSn-Dmd(mdx)/J (BL10-mdx) mouse has been the most commonly used model for Duchenne muscular dystrophy (DMD) for decades. Their muscle dysfunction and pathology is, however, less severe than in patients with DMD, which complicates preclinical studies. Recent discoveries indicate that dis...

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Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: van Putten, Maaike, Putker, Kayleigh, Overzier, Maurice, Adamzek, W. A., Pasteuning-Vuhman, Svetlana, Plomp, Jaap J., Aartsma-Rus, Annemieke
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593893/
https://ncbi.nlm.nih.gov/pubmed/30933664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802488R
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