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Fruquintinib: a novel antivascular endothelial growth factor receptor tyrosine kinase inhibitor for the treatment of metastatic colorectal cancer

Angiogenesis plays a critical role in the neoplastic growth, progression, and metastasis of colorectal cancer (CRC) in a process regulated by vascular endothelial growth factor (VEGF) family members and their receptors (VEGFR). Several small-molecule anti-VEGFR tyrosine kinase inhibitors (TKIs), suc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancer Manag Res
Hauptverfasser: Zhang, Ying, Zou, Jia-Yun, Wang, Zhe, Wang, Ying
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701622/
https://ncbi.nlm.nih.gov/pubmed/31496821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S215533
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