Detection of K-ras Mutations in Predicting Efficacy of Epidermal Growth Factor Receptor Tyrosine Kinase (EGFR-TK) Inhibitor in Patients with Metastatic Colorectal Cancer

Epidermal growth factor receptor tyrosine kinase (EGFR-TK) inhibitors are useful in treating different advanced human cancers; however, their clinical efficacy varies. This study detected K-ras mutations to predict the efficacy of EGFR-TK inhibitor cetuximab treatment on Chinese patients with metast...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Li, Ze, Liu, Xue-Wei, Chi, Zhao-Cheng, Sun, Bao-Sheng, Cheng, Ying, Cheng, Long-Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423938/
https://ncbi.nlm.nih.gov/pubmed/25950441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101019
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