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Presenilin 1 Regulates [Ca(2+)]i and Mitochondria/ER Interaction in Cultured Rat Hippocampal Neurons
Mutations in the presenilin 1 (PS1) gene are a major trigger of familial Alzheimer's disease (AD), yet the mechanisms affected by mutated PS1 causing cognitive decline are not yet elucidated. In the present study, we compared rat hippocampal neurons in culture, transfected with PS1 or with muta...
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| Gepubliceerd in: | Oxid Med Cell Longev |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Hindawi
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6701405/ https://ncbi.nlm.nih.gov/pubmed/31467635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7284967 |
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