Treatment of irritable bowel syndrome with diarrhoea using titrated ondansetron (TRITON): study protocol for a randomised controlled trial

BACKGROUND: Irritable bowel syndrome with diarrhoea (IBS-D) affects up to 4% of the general population. Symptoms include frequent, loose, or watery stools with associated urgency, resulting in marked reduction of quality of life and loss of work productivity. Ondansetron, a 5HT(3) receptor antagonis...

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Publicado en:Trials
Autores principales: Gunn, David, Fried, Ron, Lalani, Rabia, Farrin, Amanda, Holloway, Ivana, Morris, Tom, Olivier, Catherine, Kearns, Rachael, Corsetti, Maura, Scott, Mark, Farmer, Adam, Emmanuel, Anton, Whorwell, Peter, Yiannakou, Yan, Sanders, David, Mclaughlin, John, Kapur, Kapil, Eugenicos, Maria, Akbar, Ayesha, Trudgill, Nigel, Houghton, Lesley, Dinning, Phil G., Ford, Alexander C., Aziz, Qasim, Spiller, Robin
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Study Protocol
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700805/
https://ncbi.nlm.nih.gov/pubmed/31429811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-019-3562-6
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