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A model of pulldown alignments from SssI-treated DNA improves DNA methylation prediction
BACKGROUND: Protein pulldown using Methyl-CpG binding domain (MBD) proteins followed by high-throughput sequencing is a common method to determine DNA methylation. Algorithms have been developed to estimate absolute methylation level from read coverage generated by affinity enrichment-based techniqu...
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| Publicado no: | BMC Bioinformatics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6700779/ https://ncbi.nlm.nih.gov/pubmed/31426747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3011-2 |
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