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A Minor Subpopulation of Mycobacteria Inherently Produces High Levels of Reactive Oxygen Species That Generate Antibiotic Resisters at High Frequency From Itself and Enhance Resister Generation From Its Major Kin Subpopulation

Antibiotic-exposed bacteria produce elevated levels of reactive oxygen species (ROS), to which either they succumb or get mutated genome-wide to generate antibiotic resisters. We recently showed that mycobacterial cultures contained two subpopulations, short-sized cells (SCs; ∼10%) and normal/long-s...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Nair, Rashmi Ravindran, Sharan, Deepti, Ajitkumar, Parthasarathi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700507/
https://ncbi.nlm.nih.gov/pubmed/31456773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01842
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