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A Minor Subpopulation of Mycobacteria Inherently Produces High Levels of Reactive Oxygen Species That Generate Antibiotic Resisters at High Frequency From Itself and Enhance Resister Generation From Its Major Kin Subpopulation

Antibiotic-exposed bacteria produce elevated levels of reactive oxygen species (ROS), to which either they succumb or get mutated genome-wide to generate antibiotic resisters. We recently showed that mycobacterial cultures contained two subpopulations, short-sized cells (SCs; ∼10%) and normal/long-s...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Nair, Rashmi Ravindran, Sharan, Deepti, Ajitkumar, Parthasarathi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700507/
https://ncbi.nlm.nih.gov/pubmed/31456773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01842
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