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A Minor Subpopulation of Mycobacteria Inherently Produces High Levels of Reactive Oxygen Species That Generate Antibiotic Resisters at High Frequency From Itself and Enhance Resister Generation From Its Major Kin Subpopulation

Antibiotic-exposed bacteria produce elevated levels of reactive oxygen species (ROS), to which either they succumb or get mutated genome-wide to generate antibiotic resisters. We recently showed that mycobacterial cultures contained two subpopulations, short-sized cells (SCs; ∼10%) and normal/long-s...

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Publicat a:Front Microbiol
Autors principals: Nair, Rashmi Ravindran, Sharan, Deepti, Ajitkumar, Parthasarathi
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700507/
https://ncbi.nlm.nih.gov/pubmed/31456773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01842
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