PPAR Gamma-Regulated MicroRNA 199a-5p Underlies Bone Marrow Adiposity in Aplastic Anemia

Increased propensity of bone marrow-derived mesenchymal stem cells (BM-MSCs) toward adipogenic differentiation has been implicated in the fatty bone marrow and defective hematopoiesis of aplastic anemia (AA). However, the underlying molecular mechanism remains to be investigated. In this study, we f...

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Publicado en:Mol Ther Nucleic Acids
Autores principales: Zhang, Xianning, Liu, Lulu, Dou, Cuiyun, Cheng, Panpan, Liu, Lei, Liu, Haihui, Ren, Saisai, Wang, Cuiling, Jia, Shu, Chen, Lulu, Zhang, Hao, Chen, Mingtai
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700432/
https://ncbi.nlm.nih.gov/pubmed/31400610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.07.005
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