PPAR Gamma-Regulated MicroRNA 199a-5p Underlies Bone Marrow Adiposity in Aplastic Anemia

Increased propensity of bone marrow-derived mesenchymal stem cells (BM-MSCs) toward adipogenic differentiation has been implicated in the fatty bone marrow and defective hematopoiesis of aplastic anemia (AA). However, the underlying molecular mechanism remains to be investigated. In this study, we f...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Zhang, Xianning, Liu, Lulu, Dou, Cuiyun, Cheng, Panpan, Liu, Lei, Liu, Haihui, Ren, Saisai, Wang, Cuiling, Jia, Shu, Chen, Lulu, Zhang, Hao, Chen, Mingtai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700432/
https://ncbi.nlm.nih.gov/pubmed/31400610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.07.005
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