PPAR Gamma-Regulated MicroRNA 199a-5p Underlies Bone Marrow Adiposity in Aplastic Anemia

Increased propensity of bone marrow-derived mesenchymal stem cells (BM-MSCs) toward adipogenic differentiation has been implicated in the fatty bone marrow and defective hematopoiesis of aplastic anemia (AA). However, the underlying molecular mechanism remains to be investigated. In this study, we f...

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Udgivet i:Mol Ther Nucleic Acids
Main Authors: Zhang, Xianning, Liu, Lulu, Dou, Cuiyun, Cheng, Panpan, Liu, Lei, Liu, Haihui, Ren, Saisai, Wang, Cuiling, Jia, Shu, Chen, Lulu, Zhang, Hao, Chen, Mingtai
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700432/
https://ncbi.nlm.nih.gov/pubmed/31400610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.07.005
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