Mass Production of Highly Active NK Cells for Cancer Immunotherapy in a GMP Conform Perfusion Bioreactor

NK cells have emerged as promising candidates for cancer immunotherapy, especially due to their ability to fight circulating tumor cells thereby preventing metastases formation. Hence several studies have been performed to generate and expand highly cytotoxic NK cells ex vivo, e.g., by using specifi...

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Bibliografske podrobnosti
izdano v:Front Bioeng Biotechnol
Main Authors: Bröker, Katharina, Sinelnikov, Evgeny, Gustavus, Dirk, Schumacher, Udo, Pörtner, Ralf, Hoffmeister, Hans, Lüth, Stefan, Dammermann, Werner
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Bioengineering and Biotechnology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700243/
https://ncbi.nlm.nih.gov/pubmed/31457007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00194
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