Blockade of α4 integrins reduces leukocyte–endothelial interactions in cerebral vessels and improves memory in a mouse model of Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by cognitive decline associated with the deposition of amyloid-β (Aβ) plaques, hyperphosphorylation of tau protein, and neuronal loss. Vascular inflammation and leukocyte trafficking may contribute to AD pathogenesis, and a bette...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Pietronigro, Enrica, Zenaro, Elena, Bianca, Vittorina Della, Dusi, Silvia, Terrabuio, Eleonora, Iannoto, Giulia, Slanzi, Anna, Ghasemi, Somayehsadat, Nagarajan, Rajasekar, Piacentino, Gennj, Tosadori, Gabriele, Rossi, Barbara, Constantin, Gabriela
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700124/
https://ncbi.nlm.nih.gov/pubmed/31427644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48538-x
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi