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A TLR–CXCL1 pathway in DRG neurons induces neutrophil accumulation in the DRG and mechanical allodynia in EAE mice

Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system. Approximately half of the patients with MS experience severe pain; however, currently available therapeutics provide only insufficient relief. The mechanisms underlying the generation of neuropathic pain in pat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Jing, Harada, Yuka, Hayashi, Yoshinori
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700073/
https://ncbi.nlm.nih.gov/pubmed/31427756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48558-7
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