Melatonin prevents chronic intermittent hypoxia-induced injury by inducing sirtuin 1-mediated autophagy in steatotic liver of mice

BACKGROUND: Hepatic steatosis that occasionally results in nonalcoholic steatohepatitis (NASH) is related to obstructive sleep apnea (OSA). Many studies have shown that autophagy exerts protective effects on liver damage caused by various diseases and melatonin exhibits hepatoprotective properties....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sleep Breath
Prif Awduron: Ren, Jie, Jin, Meng, You, Zhen-xi, Luo, Miao, Han, Yin, Li, Guang-cai, Liu, Hui-guo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer International Publishing 2018
Pynciau:
Sleep Breathing Physiology and Disorders • Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700047/
https://ncbi.nlm.nih.gov/pubmed/30411173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11325-018-1741-4
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