Melatonin prevents chronic intermittent hypoxia-induced injury by inducing sirtuin 1-mediated autophagy in steatotic liver of mice

BACKGROUND: Hepatic steatosis that occasionally results in nonalcoholic steatohepatitis (NASH) is related to obstructive sleep apnea (OSA). Many studies have shown that autophagy exerts protective effects on liver damage caused by various diseases and melatonin exhibits hepatoprotective properties....

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Vydáno v:Sleep Breath
Hlavní autoři: Ren, Jie, Jin, Meng, You, Zhen-xi, Luo, Miao, Han, Yin, Li, Guang-cai, Liu, Hui-guo
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2018
Témata:
Sleep Breathing Physiology and Disorders • Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700047/
https://ncbi.nlm.nih.gov/pubmed/30411173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11325-018-1741-4
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