Molecular mechanisms of the sedation and analgesia induced by xylazine on Wistar rats and PC12 cell

In veterinary clinics, xylazine is commonly used as a sedative, analgesic agent that produces muscle relaxation. In this study, we aimed to explore the mechanism of action of xylazine both in vivo and in vitro. After determing the optimal dose of xylazine, 35 male Wistar rats were divided into seven...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Exp Anim
Hauptverfasser: Zhao, Jinghua, Zhang, Yiming, Liu, Wenhan, Chen, Yu, Chang, Daiyue, Zhang, Xintong, Chang, Tian, Wang, Qi, Liu, Tao, Gao, Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Japanese Association for Laboratory Animal Science 2019
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Original
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699970/
https://ncbi.nlm.nih.gov/pubmed/30956255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.18-0167
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