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Primary cilium loss in mammalian cells occurs predominantly by whole-cilium shedding

The primary cilium is a central signaling hub in cell proliferation and differentiation and is built and disassembled every cell cycle in many animal cells. Disassembly is critically important, as misregulation or delay of cilia loss leads to cell cycle defects. The physical means by which cilia are...

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Veröffentlicht in:PLoS Biol
Hauptverfasser: Mirvis, Mary, Siemers, Kathleen A., Nelson, W. James, Stearns, Tim P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699714/
https://ncbi.nlm.nih.gov/pubmed/31314751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000381
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