Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

Susceptibility to schizophrenia is inversely correlated with general cognitive ability at both the phenotypic and the genetic level. Paradoxically, a modest but consistent positive genetic correlation has been reported between schizophrenia and educational attainment, despite the strong positive gen...

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Bibliografski detalji
Izdano u:Am J Hum Genet
Glavni autori: Lam, Max, Hill, W. David, Trampush, Joey W., Yu, Jin, Knowles, Emma, Davies, Gail, Stahl, Eli, Huckins, Laura, Liewald, David C., Djurovic, Srdjan, Melle, Ingrid, Sundet, Kjetil, Christoforou, Andrea, Reinvang, Ivar, DeRosse, Pamela, Lundervold, Astri J., Steen, Vidar M., Espeseth, Thomas, Räikkönen, Katri, Widen, Elisabeth, Palotie, Aarno, Eriksson, Johan G., Giegling, Ina, Konte, Bettina, Hartmann, Annette M., Roussos, Panos, Giakoumaki, Stella, Burdick, Katherine E., Payton, Antony, Ollier, William, Chiba-Falek, Ornit, Attix, Deborah K., Need, Anna C., Cirulli, Elizabeth T., Voineskos, Aristotle N., Stefanis, Nikos C., Avramopoulos, Dimitrios, Hatzimanolis, Alex, Arking, Dan E., Smyrnis, Nikolaos, Bilder, Robert M., Freimer, Nelson A., Cannon, Tyrone D., London, Edythe, Poldrack, Russell A., Sabb, Fred W., Congdon, Eliza, Conley, Emily Drabant, Scult, Matthew A., Dickinson, Dwight, Straub, Richard E., Donohoe, Gary, Morris, Derek, Corvin, Aiden, Gill, Michael, Hariri, Ahmad R., Weinberger, Daniel R., Pendleton, Neil, Bitsios, Panos, Rujescu, Dan, Lahti, Jari, Le Hellard, Stephanie, Keller, Matthew C., Andreassen, Ole A., Deary, Ian J., Glahn, David C., Malhotra, Anil K., Lencz, Todd
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699140/
https://ncbi.nlm.nih.gov/pubmed/31374203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.06.012
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