Structures of single‐layer β‐sheet proteins evolved from β‐hairpin repeats

Free‐standing single‐layer β‐sheets are extremely rare in naturally occurring proteins, even though β‐sheet motifs are ubiquitous. Here we report the crystal structures of three homologous, single‐layer, anti‐parallel β‐sheet proteins, comprised of three or four twisted β‐hairpin repeats. The struct...

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Veröffentlicht in:Protein Sci
Hauptverfasser: Xu, Qingping, Biancalana, Matthew, Grant, Joanna C., Chiu, Hsiu‐Ju, Jaroszewski, Lukasz, Knuth, Mark W., Lesley, Scott A., Godzik, Adam, Elsliger, Marc‐André, Deacon, Ashley M., Wilson, Ian A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699103/
https://ncbi.nlm.nih.gov/pubmed/31306512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3683
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