Pathogenic and Protective Autoantibodies in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED)

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a rare disorder caused by mutations in the autoimmune regulator (AIRE) gene, leading to defects in T cell selection. The disease manifestations include both autoimmune tissue destruction and immunodeficiency, with specific su...

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Bibliografiske detaljer
Udgivet i:Antibodies (Basel)
Main Authors: Kashem, Sakeen W., Binstadt, Bryce A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698825/
https://ncbi.nlm.nih.gov/pubmed/31548517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib6010001
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