Parallel G-triplexes and G-hairpins as potential transitory ensembles in the folding of parallel-stranded DNA G-Quadruplexes

Guanine quadruplexes (G4s) are non-canonical nucleic acids structures common in important genomic regions. Parallel-stranded G4 folds are the most abundant, but their folding mechanism is not fully understood. Recent research highlighted that G4 DNA molecules fold via kinetic partitioning mechanism...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Stadlbauer, Petr, Kührová, Petra, Vicherek, Lukáš, Banáš, Pavel, Otyepka, Michal, Trantírek, Lukáš, Šponer, Jiří
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Computational Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698752/
https://ncbi.nlm.nih.gov/pubmed/31318975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz610
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